Spotlight on CRISPR in Strongyloides Parasitic Nematodes.
نویسنده
چکیده
Parasitic nematodes are biomedically and economically important, but many are genetically intractable which limits our understanding of their molecular and cellular biology. Gang et al. report CRISPR/Cas9 genome editing in parasites of the genus Strongyloides, generating both knock-outs and knock-ins, and demonstrated heritability of the modifications, a crucial advance in the field.
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عنوان ژورنال:
- Trends in parasitology
دوره 34 1 شماره
صفحات -
تاریخ انتشار 2018